Product Safety

Fordays Product Safety Overview

Our major supplements such as the Natural DN Collagen are regularly tested for toxicity and radioactivity to confirm its safety.

We carry out human patch tests and allergy tests for all cosmetic products.

Natural DN Collagen

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>20mL/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

4-week repeated oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidelines for Designation of Food Additives and Revision of Usage Standards" (March 22, 1996 No. 29)
Results NOAEL>10mL/kg/day
No fatalities, abnormalities, and weight abnormalities. No abnormal findings were observed by hematological examination, histological examination, etc., and no toxicity was shown.

Umu Test (Presence or absence of DNA damage)

Testing Body Food and Drug Safety Center
Safety rules regarding the use of genetically modified organisms, etc. "Act on Ensuring Biodiversity by Regulation of Genetically Modified Organisms" (June 18, 2003, Act No. 97) "Safety Management Regulations on the Use of Genetically Modified Organisms, etc., Food and Drug Safety Center" (April 1, 2019) (Approval number: R2020-02A)
"Safety Management Regulations on the Use of Genetically Modified Organisms, etc., Food and Drug Safety Center" (April 1, 2019) (Approval number: R2020-02A)
Results Not DNA damaging (negative)

"Subject: Product Manufactured in December 2020, January 2021 (9th Generation)"

We regularly strive to ensure product safety with our well-established quality control system. Since the Great East Japan Earthquake, we report on confirmations of radioactive substances at the raw material supply destinations to provide further safety and assurance to our customers.

Fcore-2021 (salmon milt extract containing DNA)

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>20mL/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

4-week repeated oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidelines for Designation of Food Additives and Revision of Usage Standards" (March 22, 1996 No. 29)
Results NOAEL>10mL/kg/day
No fatalities, abnormalities, and weight abnormalities. No abnormal findings were observed by hematological examination, histological examination, etc., and no toxicity was shown.

Umu Test (Presence or absence of DNA damage)

Testing Body Food and Drug Safety Center
Safety rules regarding the use of genetically modified organisms, etc. "Act on Ensuring Biodiversity by Regulation of Genetically Modified Organisms" (June 18, 2003, Act No. 97)
"Safety Management Regulations on the Use of Genetically Modified Organisms, etc., Food and Drug Safety Center" (April 1, 2019) (Approval number: R2020-02A)
Results Not DNA damaging (negative)

"Subject: Product Manufactured in January 2021"

Aren SP

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

4-week repeated oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidelines for Designation of Food Additives and Revision of Usage Standards" (March 22, 1996 No. 29)
Results NOAEL>1,000mg/kg/day
No fatalities, abnormalities, and weight abnormalities. No abnormal findings were observed by hematological examination, histological examination, etc., and no toxicity was shown.

Reversion Test (Ames Test)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidance on Genetic Toxicity Testing and Interpretation of Pharmaceuticals" (September 20, 2012, Pharmaceutical and Food Safety Examination No. 0920 No.2) "OECD Guidelines for the Testing of Chemical Substances 471, Reversion Mutation Testing Using Bacteria" (OECD TG 471, July 21 1997)
Results Negative
(No gene mutagenesis detected)

"Subject: Product Manufactured in March 2018"

Mousa Essence Drink SNOWy

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>20mL/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

4-week repeated oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidelines for Designation of Food Additives and Revision of Usage Standards" (March 22, 1996 No. 29)
Results NOAEL>10mL/kg/day
No fatalities, abnormalities, and weight abnormalities. No abnormal findings were observed by hematological examination, histological examination, etc., and no toxicity was shown.

Reversion Test (Ames Test)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidance on Genetic Toxicity Testing and Interpretation of Pharmaceuticals" (September 20,2012, Pharmaceutical and Food Safety Examination No. 0920 No.2)
"OECD Guidelines for the Testing of Chemical Substances 471, Reversion Mutation Testing Using Bacteria" (OECD TG 471, July 21 1997)
Results Negative
(No gene mutagenesis detected)

"Subject: Product Manufactured in January 2019"

Immuno Vital HI

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

4-week repeated oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidelines for Designation of Food Additives and Revision of Usage Standards" (March 22, 1996 No. 29)
Results NOAEL>1,000mg/kg/day
No fatalities, abnormalities, and weight abnormalities. No abnormal findings were observed by hematological examination, histological examination, etc., and no toxicity was shown.

"Subject: Product Manufactured in October 2019"

Amino Acty EX BCAA & Glutamine Plus

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

"Subject: Product Manufactured in October 2019"

Red DHA

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

"Subject: Product Manufactured in October 2019"

Fiber Mix Bio (Food with Function Claims)

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

4-week repeated oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidelines for Designation of Food Additives and Revision of Usage Standards" (March 22, 1996 No. 29)
Results NOAEL>1,000mg/kg/day
No fatalities, abnormalities, and weight abnormalities. No abnormal findings were observed by hematological examination, histological examination, etc., and no toxicity was shown.

"Subject: Product Manufactured in August 2017"

I Refre Clear (Food with Function Claims)

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

4-week repeated oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method "Guidelines for Designation of Food Additives and Revision of Usage Standards" (March 22, 1996 No. 29)
Results NOAEL>1,000mg/kg/day
No fatalities, abnormalities, and weight abnormalities. No abnormal findings were observed by hematological examination, histological examination, etc., and no toxicity was shown.

"Subject: Product Manufactured in October 2017"

Good Night (Food with Function Claims)

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

"Subject: Product Manufactured in October 2018"

J Charge (Food with Function Claims)

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

"Subject: Product Manufactured in May 2019"

Kioku no Kiwami (Food with Function Claims)

Test Type: Toxicity Test

Single dose oral toxicity test (rat)

Testing Body Food and Drug Safety Center
Guidelines/Testing Method Drug toxicity test method guidelines [1] Single-dose toxicity study (September 11, 1989, Drug Trial No. 24, August 10, 1993, New Drug No. 88)
Results LD50>2,000mg/kg
No fatalities, abnormalities, and weight abnormalities detected. No abnormal findings were observed by pathological autopsy and no acute toxicities were shown.

"Subject: Product Manufactured in August 2020"